BY SAMEER REDDY

Beaches, bikinis and feathered headdresses are not reasons to visit the biggest city in Brazil—that's Rio you're dreaming of. What São Paulo lacks in sea and sand, it more than makes up for with sophisticated style, can't-look-away architecture and a rich culture influenced by immigrants from around the globe.

This megatropolis of 11 million is the pounding heart of South America's biggest economic success story. A city on the make, it's dynamic and teeming, yet noticeably…happy. Despite the frequently rainy weather, locals have a rep for offering easy smiles.

And why not? Paulistas are blessed with stunning buildings, including several ...